- From I-75 take the Fruitville Road exit and proceed west to Orange Ave and make a left turn. From there you will go 3 blocks to Main Street and turn right (west). Stay on Main Street (go through Lemon Ave. intersection and the 5 Points intersection) for 2.5 blocks. Main Street Bistro is located at 1345 Main Street which is on your right (north) side of the street.
- From US 41 turn east on Main Street pass through the intersection of Gulf Stream then though the intersection of Palm and Main Street. The Bistro is on your left.
We are centrally located in downtown Sarasota, at the west end of Main Street.
Click here for a printable map.